How many HDD are you running? Set to spin down or no? Those spinning all the time add up quickly.
Sleep state and power States are different things… I’ve never heard of power profiles causing issues. I’d try keeping sleep disabled in BIOS and then look into what you need to change to allow the processor to idle/downclock. There’s no reason this shouldn’t work I’m aware of.
Could try undervolting as well.
You could try llamaCPP, I think its configured to run better on cpu’s