I’ll add in that Kino’s Journey was originally a light novel series, キノの旅 (Kino no Tabi). I never actually saw the anime, but really enjoyed the light novels (I read them in Japanese; hopefully the English translation is equally good).
I think Kino is a great series for anyone who enjoys dystopias and social commentary. It’s a bit like The Twilight Zone or Black Mirror with its episodic premise of “imagine if there were a society that functioned like [concept of the week]; wouldn’t that be interesting/weird/fucked up?” Definitely not your standard anime/light novel! And yes, the tone of TEW and Kino is completely different; as mentioned in another comment, the similarity is in the setting/premise of exploring different isolated communities that each have some bizarre unique feature.
Ten or fifteen years ago I almost certainly would not have found the girls as bland and annoying as I do watching this today. I think a combination of having read/watched dozens of series with similar characters, as well as aging out of the teenage/young adult demographic, made me completely uninterested in these characters… to the point that watching TEW felt like I was unironically “watching it for the plot”: I’m just here for the trains, bizarre setting, and surreal vibe!
This is entirely a matter of opinion, of course. However of the people I know aged 30 and up who watch anime, I don’t think most of them would particularly enjoy the girls, and most likely would shy away from the series specifically because of their presence. That’s generally the type of audience I write reviews for; these reviews are posted to the “Animation and Comics after 30” community first and cross-posted here when relevant. Once upon a time I was into “cute girls find cute things series” (I re-watched Lucky Star at least once), but tastes change as you age, and while some older viewers may still enjoy these characters, I definitely did not.
One series I am really interested in this season is Dead Dead Demon’s Dededededestruction, in part because the teenage girl cast don’t look or act like stereotypical anime girls. Compared to most anime girls, it’s almost as if the manga author pulled an Alien and wrote the characters to be gender neutral, since they often act more how I’d expect teenage boys in anime to act. Watching this series reminds me of watching the live action series Derry Girls: here’s a cast that compared to most media feels like a real-life group of teenagers, awkward and weird. I don’t think the manga quite translates to the animated format, but that’s a topic for a separate review.