Does your router have an app or way of letting you remotely see if the server is even showing on your home network?? It could be a physical disconnect or Ethernet port failure, or NIC failure maybe? A reboot wouldn’t help if the issue was related to something like that.
Edit: Actually, re-read your post and thinking about this again, what I said wouldn’t make sense…
You could have some sort of corruption causing an error in the appdata, preventing it from running. Might be a RAM issue.
I edited my original post right when you replied, my bad.
I dunno if you can do that much remotely, honestly. I kinda feel like something might have corrupted? What kinda system are you using? Any more details you can provide?