I’m thinking about buying a Raspberry Pi to start my self-hosted journey. I have three usecases in mind: Navidrome server, Jellyfin server and a Pi-hole network ad-blocking. Can a single machine (like a Raspberry Pi) run these operations simultaneously? Thanks in advance!


Up until the point the resources available (CPU/ram/storage) become a problem.
That said, managing those apps as installations can be troublesome, which is why people like podman/docker. Updates are more contained, system updates don’t break services, and vice-versa.
A more comprehensive option is to use Proxmox or similar to manage services as a combination of Virtual Machines, LXC’S (Linux containers), and maybe podman/docker on a VM. Note that Proxmox techincally supports importing a docker container as an LXC, but this is a one-time action. Not recommended. (EDIT: For the record, there is a Proxmox on pi effort, but its community supported not Proxmox supported as of the last time I looked.)
Navidrome and pihole are the easy ones on that list also. Jellyfin itself is easy, but you aren’t going to be transcoding video on the fly, so make sure its in a format that is friendly to all of your devices, transcoding in advance if needed.